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Article

Dynamics of CD8 T-Cell Activation After Discontinuation of HIV Treatment Intensification

8 Feb 2013

Abstract excerpt

BACKGROUND: Detection of episomal HIV cDNA has been associated with greater levels of CD8 and CD4 T-cell activation in HIV-1-infected highly active antiretroviral therapy (HAART)-suppressed individuals. However, HAART intensification exclusively reduced CD8 T-cell activation. METHODS: We evaluated activation markers 12 weeks after raltegravir withdrawal in a previously described 48-week raltegravir...

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PMID: 23392458
DOI: 10.1097/qai.0b013e318289439a

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