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Article

Close association of CD8<sup>+</sup>/CD38<sup>bright</sup> with HIV‐1 replication and complex relationship with CD4<sup>+</sup> T‐cell count

12 Dec 2008

Abstract excerpt

BACKGROUND: Measuring lymphocyte activation provides information in addition to CD4(+) T-cell count for immune monitoring of HIV-1 infected patients. CD38 is a well-established activation marker that is generally analyzed on the whole population of CD8(+) T-cells. Focusing specifically on CD38 high expression (CD8(+)/CD38(bright)) may be an interesting surrogate gating strategy because CD38(bright) characterizes...

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PMID: 19072838
DOI: 10.1002/cyto.b.20467

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