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Article

Introduction of site-specific mutations into the genome of influenza virus.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 1990

Enami M, Luytjes W, Krystal M, Palese P

Abstract excerpt

We succeeded in rescuing infectious influenza virus by transfecting cells with RNAs derived from specific recombinant DNAs. RNA corresponding to the neuraminidase (NA) gene of influenza A/WSN/33 (WSN) virus was transcribed in vitro from plasmid DNA and, following the addition of purified influenza virus RNA polymerase complex, was transfected into MDBK cells. Superinfection with helper virus lacking the WSN NA...

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Identifiers

PMID: 2339122
DOI: 10.1073/pnas.87.10.3802
PMCID: PMC53991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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