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Engineering influenza viral vectors

20 Dec 2012

Abstract excerpt

The influenza virus is a respiratory pathogen with a negative-sense, segmented RNA genome. Construction of recombinant influenza viruses in the laboratory was reported starting in the 1980s. Within a short period of time, pioneer researchers had devised methods that made it possible to construct influenza viral vectors from cDNA plasmid systems. Herein, we discuss the evolution of influenza virus reverse...

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PMID: 22922205
DOI: 10.4161/bioe.21950

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