Article
Nano-RECall provides an integrated pipeline for HIV-1 drug resistance testing from Oxford Nanopore sequence data.
Tropical medicine & international health : TM & IH - 1 Mar 2023
Delaney Kayla Eileen, Ngobeni Trevor, Woods Conan K, Gordijn Carli, Claassen Mathilda, Parikh Urvi, Harrigan P Richard, van Zyl Gert Uves
Abstract excerpt
OBJECTIVES: Low-capital-layout sequencing options from Oxford Nanopore Technologies (ONT) could assist in expanding HIV drug resistance testing to resource-limited settings. HIV drug resistance mutations often occur as mixtures, but current ONT pipelines provide a consensus sequence only. Moreover, there is no integrated pipeline that provides a drug resistance report from an ONT sequence file without...
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