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Article

Ion Torrent Genexus as a Fast and Reliable Solution for HIV-1 Drug Resistance Testing: Comparison with the GeneStudio S5 Workflow.

International journal of molecular sciences - 15 Jul 2026

Smoquina Flavia, Forbici Federica, Berno Giulia, Rueca Martina, Amendola Alessandra, Sberna Giuseppe, Brillo Fabiano, Lazzari Elisabetta, Abbate Isabella, Rozera Gabriella, Sarti Silvia, Gagliardini Roberta, Mazzotta Valentina, Antinori Andrea, Maggi Fabrizio, Fabeni Lavinia

Abstract excerpt

Next-generation sequencing (NGS) has improved HIV-1 genotypic resistance testing (GRT) by enabling the detection of minority drug-resistance variants, although interpretation of low-frequency mutations remains challenging because of sequencing artifacts. This study compared the analytical performance and workflow efficiency of two Ion Torrent platforms, GeneStudio S5 (S5) and Genexus (GX), for routine HIV-1 GRT....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42511650
DOI: 10.3390/ijms27146307
PMCID: PMC13410318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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