Article
Promises and pitfalls of Illumina sequencing for HIV resistance genotyping.
Virus research - 15 Jul 2017
Brumme Chanson J, Poon Art F Y
Abstract excerpt
Genetic sequencing ("genotyping") plays a critical role in the modern clinical management of HIV infection. This virus evolves rapidly within patients because of its error-prone reverse transcriptase and short generation time. Consequently, HIV variants with mutations that confer resistance to one or more antiretroviral drugs can emerge during sub-optimal treatment. There are now multiple HIV drug resistance...
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