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Article

Development and characterization of a bladder cancer xenograft model using patient-derived tumor tissue.

Cancer science - 1 May 2013

Park Bumsoo, Jeong Byong Chang, Choi Yoon-La, Kwon Ghee Young, Lim Joung Eun, Seo Seong Il, Jeon Seong Soo, Lee Hyun Moo, Choi Han Yong, Lee Kyu-Sung

Abstract excerpt

Most of the cancer xenograft models are derived from tumor cell lines, but they do not sufficiently represent clinical cancer characteristics. Our objective was to develop xenograft models of bladder cancer derived from human tumor tissue and characterize them molecularly as well as histologically. A total of 65 bladder cancer tissues were transplanted to immunodeficient mice. Passagable six cases with...

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Identifiers

PMID: 23384396
DOI: 10.1111/cas.12123
PMCID: PMC7657213

Genes

BRAF
CTNNB1
HRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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