Article

Bladder cancer organoids as a functional system to model different disease stages and therapy response

2022-06-27

Abstract excerpt

<title>Abstract</title> <p>Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment failure, suggesting that patients could benefit from a more personalized treatment approach. Patient-derived organoids (PDOs) have been successfully used as a functional model for predicting drug response in different cancers. In our study, we established PDO cultures from different BLCa stages. PDOs pre...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 36d525c7-7d48-55a5-83fe-5eef2dd23ec0
DOI: 10.21203/rs.3.rs-1758183/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bladder cancer organoids as a functional system to model different disease stages and therapy responseDOI 10.21203/rs.3.rs-1758183/v1Read

Bladder cancer organoids as a functional system to model different disease stages and therapy responseSemantic proximity Read

Bladder cancer organoids as a functional system to model different disease stages and therapy responseSemantic proximity Read

Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer.Semantic proximity Read

Urine-derived bladder cancer organoids (urinoids) as tool for cancer longitudinal response monitoring and therapy adaptationSemantic proximity Read

Bridging phenotype and function in bladder cancer using immuno-competent organoids and ex vivo drug screening.Semantic proximity Read

A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid cultureSemantic proximity Read

Patient‐Derived Upper Tract Urothelial Carcinoma Organoids as a Platform for Drug ScreeningSemantic proximity Read

FOLLOW-U; study protocol evaluating oncological systemic treatment response of advanced bladder cancer patients using urinoidsSemantic proximity Read

Patient-derived urachal cancer organoids for personalized drug screeningSemantic proximity Read

Pancreatic cancer patient-derived organoids capture therapy response and tumor evolutionSemantic proximity Read

Integrative Drug Screening and Multiomic Characterization of Patient-derived Bladder Cancer Organoids Reveal Novel Molecular Correlates of Gemcitabine ResponseSemantic proximity Read

Establishing a Canine Urothelial Organoid Repository: A Platform for Comparative and Translational Carcinoma StudiesSemantic proximity Read