Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer.

Genes, chromosomes & cancer - 1 Mar 2000

Gildea J J, Golden W L, Harding M A, Theodorescu D

Abstract excerpt

There has been a general lack of human paired cell lines that both reproduce the in vivo spectrum of tumor progression of bladder cancer and have some of the genetic changes associated with progression in human tumor tissue. T24, a cell line established from an invasive human transitional cell carcinoma (TCC) of the bladder, has been used extensively in bladder cancer research. However, a significant limitation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Transitional Cell
Share to Cell Count
Share to Metalloendopeptidases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Mice, SCID

Share to Neoplasm Transplantation

Share to Tumor Stem Cell Assay

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 10679914
DOI: 10.1002/(sici)1098-2264(200003)27:3<252::aid-gcc5>3.0.co;2-9

Genes

HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer.PMID 10679914Read ↗

Development and characterization of a bladder cancer xenograft model using patient-derived tumor tissue.Semantic proximity Read ↗

Integrated genomic and transcriptional analysis of the in vitro evolution of telomerase-immortalized urothelial cells (TERT-NHUC).Semantic proximity Read ↗

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.Semantic proximity Read ↗

Re: A Genetically Defined Disease Model Reveals that Urothelial Cells Can Initiate Divergent Bladder Cancer Phenotypes.Semantic proximity Read ↗

Re: A Genetically Defined Disease Model Reveals That Urothelial Cells Can Initiate Divergent Bladder Cancer Phenotypes.Semantic proximity Read ↗

The Role of TKS5 in Chromosome Stability and Bladder Cancer ProgressionSemantic proximity Read ↗

Characterization of two urothelium cancer cell lines derived from a blackfoot disease endemic area in Taiwan.Semantic proximity Read ↗

Molecular evolution of multiple recurrent cancers of the bladder.Semantic proximity Read ↗

Phenotypic and cytogenetic characterization of human bladder urothelia expanded in vitro.Semantic proximity Read ↗

Human bladder carcinoma cell lines as indicators of oncogenic change relevant to urothelial neoplastic progression.Semantic proximity Read ↗

Genetic and Molecular Markers of Urothelial Premalignancy and MalignancySemantic proximity Read ↗

Forerunner genes contiguous to RB1 contribute to the development of <i>in situ</i> neoplasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.