Article
Sulphamethoxazole acetylation in fast and slow acetylators.
International journal of clinical pharmacology, therapy, and toxicology - 1 Apr 1990
Bozkurt A, Basci N E, Isimer A, Tuncer M, Erdal R, Kayaalp S O
Abstract excerpt
Acetylation of sulphamethoxazole was studied in 22 subjects previously phenotyped with sulphadimidine. Sulphamethoxazole and its acetylated metabolite were measured in 6 h plasma and 0-6 h urine samples. Percentage of plasma acetylated-sulphamethoxazole did not correlate with the percentage of urinary acetylated-sulphamethoxazole. There was also no correlation between the percentage of acetylated-sulphadimidine...
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