Article
N-acetylation in healthy and diseased children.
European journal of clinical pharmacology - 1 Jan 1990
Hadasová E, Brysová V, Kadlcáková E
Abstract excerpt
Acetylation capacity was examined in three groups of Czech children by measuring the plasma and urine concentrations of sulphamethazine and its acetylated metabolite 6 h after an oral test dose of 20 mg/kg sulphamethazine. Amongst 82 healthy children aged 4-15 y there were 32 (39%) fast acetylators; there was no significant difference between the number of boys and girls, or between children over or less than 6...
Topics
- Acetylation
- Adolescent
- Aging
- Child
- Child, Preschool
- Czechoslovakia
- Diabetes Mellitus, Type 1
- Female
- Humans
- Male
- Metabolism, Inborn Errors
- Pharmaceutical Preparations