Article
Synergistic effects of A1896, T1653 and T1762/A1764 mutations in genotype c2 hepatitis B virus on development of hepatocellular carcinoma.
Journal of viral hepatitis - 1 Mar 2013
Lyu H, Lee D, Chung Y-H, Kim J A, Lee J-H, Jin Y-J, Park W, Mathews P, Jaffee E, Zheng L, Yu E, Lee Y J
Abstract excerpt
The effects of genomic changes in hepatitis B virus (HBV) on the occurrence of hepatocellular carcinoma (HCC) are still unclear, especially in relation to the genotype of HBV. In this study, we examined the effects of genomic changes in HBV of genotype C2 on the development of HCC. A total of 318 patients with HBV-associated HCC and 234 patients with chronic hepatitis B (CHB) were studied. All of HCC cases were...
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