Article
Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae.
PloS one - 1 Jan 2013
Michaillat Lydie, Mayer Andreas
Abstract excerpt
The equilibrium of membrane fusion and fission influences the volume and copy number of organelles. Fusion of yeast vacuoles has been well characterized but their fission and the mechanisms determining vacuole size and abundance remain poorly understood. We therefore attempted to systematically characterize factors necessary for vacuole fission. Here, we present results of an in vivo screening for deficiencies in...
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