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Article

Cross-species comparison of site-specific evolutionary-rate variation in influenza haemagglutinin.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Mar 2013

Meyer Austin G, Dawson Eric T, Wilke Claus O

Abstract excerpt

We investigate the causes of site-specific evolutionary-rate variation in influenza haemagglutinin (HA) between human and avian influenza, for subtypes H1, H3, and H5. By calculating the evolutionary-rate ratio, ω = dN/dS as a function of a residue's solvent accessibility in the three-dimensional protein structure, we show that solvent accessibility has a significant but relatively modest effect on site-specific...

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Source

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Identifiers

PMID: 23382434
DOI: 10.1098/rstb.2012.0334
PMCID: PMC3678335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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