Article
Pharmacogenetics of allopurinol--making an old drug safer.
Journal of clinical pharmacology - 1 Jul 2013
Lam May P S, Yeung Chi K, Cheung Bernard M Y
Abstract excerpt
Allopurinol is a drug that has been used for decades to lower serum urate levels in patients with gout or chronic renal failure and in cancer patients undergoing chemotherapy at risk of tumor lysis syndrome. Patients may develop cutaneous hypersensitivity reactions, ranging from mild rashes to potentially fatal severe cutaneous adverse reactions (SCARs) namely drug hypersensitivity syndrome, Stevens-Johnson...
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