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Article

Association between PCSK9 and LDLR gene polymorphisms with coronary heart disease: case-control study and meta-analysis.

Clinical biochemistry - 1 Jun 2013

Zhang Lina, Yuan Fang, Liu Panpan, Fei Lijuan, Huang Yi, Xu Limin, Hao Lingmei, Qiu Xujun, Le Yanping, Yang Xi, Xu Weifeng, Huang Xiaoyan, Ye Meng, Zhou Jianqing, Lian Jiangfang, Duan Shiwei

Abstract excerpt

OBJECTIVE: To explore the association of rs11206510 (PCSK9 gene) and rs1122608 (LDLR gene) polymorphisms with coronary heart disease (CHD) in Han Chinese. METHODS: A total of 813 participants (290 CHD cases, 193 non-CHD controls and 330 healthy controls) were recruited in the case-control study. DNA genotyping was performed on the SEQUENOM® Mass-ARRAY iPLEX® platform. χ(2)-test was used to compare the genotype...

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Source

Identifiers

PMID: 23380588
DOI: 10.1016/j.clinbiochem.2013.01.013

Genes

LDLR
PCSK9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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