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Article

Genetic polymorphisms in LDLR, APOB, PCSK9 and other lipid related genes associated with familial hypercholesterolemia in Malaysia.

PloS one - 1 Jan 2013

Lye Say-Hean, Chahil Jagdish Kaur, Bagali Pramod, Alex Livy, Vadivelu Jamunarani, Ahmad Wan Azman Wan, Chan Siew-Pheng, Thong Meow-Keong, Zain Shamsul Mohd, Mohamed Rosmawati

Abstract excerpt

Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevations in total cholesterol (TC) and low density lipoprotein cholesterol (LDLc). Development of FH can result in the increase of risk for premature cardiovascular diseases (CVD). FH is primarily caused by genetic variations in Low Density Lipoprotein Receptor (LDLR), Apolipoprotein B (APOB) or Proprotein Convertase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23593297
DOI: 10.1371/journal.pone.0060729
PMCID: PMC3620484

Genes

APOB
LDLR
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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