Article
Meta-analysis of low density lipoprotein receptor (LDLR) rs2228671 polymorphism and coronary heart disease.
BioMed research international - 1 Jan 2014
Ye Huadan, Zhao Qianlei, Huang Yi, Wang Lingyan, Liu Haibo, Wang Chunming, Dai Dongjun, Xu Leiting, Ye Meng, Duan Shiwei
Abstract excerpt
Low density lipoprotein receptor (LDLR) can regulate cholesterol metabolism by removing the excess low density lipoprotein cholesterol (LDL-C) in blood. Since cholesterol metabolism is often disrupted in coronary heart disease (CHD), LDLR as a candidate gene of CHD has been intensively studied. The goal of our study is to evaluate the overall contribution of LDLR rs2228671 polymorphism to the risk of CHD by...
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