Article
A replication study and a meta-analysis of the association between the CDKN2A rs1333049 polymorphism and coronary heart disease.
Journal of atherosclerosis and thrombosis - 1 Jan 2014
Lian Jiangfang, Ba Yanna, Dai Dongjun, Chen Zhikui, Lou Yumei, Jiang Qingjun, Zhao Ruochi, Sun Liqin, Huang Xiaoyan, Yang Xi, Ye Ming, Wang Ying, Mao Haiyan, Guan Haiwang, Xu Limin, Guo Jian, Fang Peiliang, Li Junxin, Ye Huadan, Chen Xiaoliang, Peng Ping, Zhou Jianqing, Duan Shiwel
Abstract excerpt
AIM: The aim of this study was to assess whether rs1333049 was associated with coronary heart disease (CHD) in Han Chinese. METHODS: This case-control study was involved with 599 CHD patients and 591 non-CHD controls. Meanwhile, a comprehensive meta-analysis was also conducted to establish the contribution of rs1333049 to CHD. RESULTS: Our results showed that rs1333049 increased the risk of CHD by 38% (OR=1.38,...
Read the complete abstract on PubMed