Article
New insights into the pathogenesis of membranous glomerulonephritis
11 Apr 2006
Abstract excerpt
PURPOSE OF REVIEW: Membranous nephropathy is one of the most common glomerulopathies. Current treatments are entirely empirical, and concept-driven therapies are dramatically lacking. This review focuses on new pathophysiologic aspects of the disease, with special emphasis on the antigenic targets of pathogenic antibodies. RECENT FINDINGS: Neutral endopeptidase - a podocyte antigen that can digest biologically...
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