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Article

Immunoglobulin genes influence the magnitude of humoral immunity to cytomegalovirus glycoprotein B.

The Journal of infectious diseases - 1 Dec 2014

Pandey Janardan P, Kistner-Griffin Emily, Radwan Faisal F, Kaur Navtej, Namboodiri Aryan M, Black Laurel, Butler Mary Ann, Carreón Tania, Ruder Avima M

Abstract excerpt

Human cytomegalovirus (HCMV) is a risk factor for many human diseases, but among exposed individuals, not everyone is equally likely to develop HCMV-spurred diseases, implying the presence of host genetic factors that might modulate immunity to this virus. Here, we show that antibody responsiveness to HCMV glycoprotein B (gB) is significantly associated with particular immunoglobulin GM (γ marker) genotypes....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, Immunoglobulin

Share to Immunity, Humoral

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Source

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Identifiers

PMID: 24973460
DOI: 10.1093/infdis/jiu367
PMCID: PMC4296192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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