Article
Point mutations at codon 12 of C-K-ras in human endometrial carcinomas.
Cancer letters - 15 May 1990
Lester D R, Cauchi M N
Abstract excerpt
Samples of human endometrial carcinomas of ranging degree of histological differentiation, and normal endometrial tissues were screened for the presence of single site DNA mutations at codon 12 of the C-K-ras gene using oligonucleotide hybridisation of DNA amplified by the polymerase chain reaction (PCR). Two instances of base substitution were detected; one resulting in a GLY-ALA amino acid replacement in a well...
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