Article
Two-dimensional fluorescence in-gel electrophoresis of coronary restenosis tissues in minipigs: increased adipocyte fatty acid binding protein induces reactive oxygen species-mediated growth and migration in smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2013
Lu Lin, Wang Ya Nan, Sun Wei Hua, Liu Zhu Hui, Zhang Qi, Pu Li Jin, Yang Ke, Wang Ling Jie, Zhu Zhen Bin, Meng Hua, Yang Ping, Du Run, Chen Qiu Jing, Wang Li Shun, Yu Hong, Shen Wei Feng
Abstract excerpt
OBJECTIVE: We aimed to uncover the protein changes of coronary artery in-stent restenosis (ISR) tissue in minipigs with and without streptozotocin-induced diabetes mellitus by quantitative 2-dimensional fluorescence in-gel electrophoresis (2D-DIGE), and to investigate the influences of crucial proteins identified, particularly adipocyte fatty acid binding protein (AFABP), in human arterial smooth muscle cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.