Article
Farm-derived Gram-positive bacterium Staphylococcus sciuri W620 prevents asthma phenotype in HDM- and OVA-exposed mice.
Allergy - 1 Mar 2013
Hagner S, Harb H, Zhao M, Stein K, Holst O, Ege M J, Mayer M, Matthes J, Bauer J, von Mutius E, Renz H, Heine H, Pfefferle P I, Garn H
Abstract excerpt
BACKGROUND: Farm-derived dust samples have been screened for bacteria with potential allergo-protective properties. Among those was Staphylococcus sciuri W620 (S. sciuri W620), which we tested with regard to its protective capacities in murine models of allergic airway inflammation. METHODS: We employed two protocols of acute airway inflammation in mice administering either ovalbumin (OVA) or house dust mite...
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