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Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33

25 Sept 2020

Abstract excerpt

Staphylococcus aureus can secrete a broad range of virulence factors, among which staphylococcal serine protease-like proteins (Spls) have been identified as bacterial allergens. The S. aureus allergen serine protease-like protein D (SplD) induces allergic asthma in C57BL/6J mice through the IL-33/ST2 signalling axis. Analysis of C57BL/6J, C57BL/6N, CBA, DBA/2 and BALB/c mice treated with intratracheal...

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PMID: 33072128
DOI: 10.3389/fimmu.2020.582044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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