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Article

Spon2 knockdown suppresses the phenotype of house dust mite-induced allergic asthma in mice and cells.

Immunologic research - 21 Jul 2025

Zheng Haihan, Ding Shenggang, Rong Daoxiang, Li Ting, Xiong Mei

Abstract excerpt

Allergic asthma is a chronic inflammatory disease of the airways. The objective of this study was to identify potential therapeutic targets for allergic asthma through RNA sequencing (RNA-seq) and experimental analyses. Allergic asthma models, both in cells and mice, were induced using house dust mite (HDM) treatment. RNA-seq analysis of lung tissues from HDM-induced allergic asthma mice and control mice was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40691739
DOI: 10.1007/s12026-025-09641-6

Genes

CD80
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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