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Article

Genomic heterogeneity in acute leukemia.

Cytogenetic and genome research - 1 Jan 2013

Paulsson K

Abstract excerpt

Acquired genetic aberrations are the underlying cause of leukemogenesis in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The karyotypes of AML and ALL cases are generally quite simple as seen by chromosome banding analysis, with few genetic changes and a limited number of subclones. However, investigations using fluorescence in situ hybridization, loss of heterozygosity analysis,...

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Share to Chromosomal Instability
Share to Genome, Human
Share to In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Loss of Heterozygosity

Share to Mice, Transgenic

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Identifiers

PMID: 23363651
DOI: 10.1159/000346797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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