Article
Common mitochondrial sequence variants in ischemic stroke.
Annals of neurology - 1 Mar 2011
Anderson Christopher D, Biffi Alessandro, Rahman Rosanna, Ross Owen A, Jagiella Jeremiasz M, Kissela Brett, Cole John W, Cortellini Lynelle, Rost Natalia S, Cheng Yu-Ching, Greenberg Steven M, de Bakker Paul I W, Brown Robert D, Brott Thomas G, Mitchell Braxton D, Broderick Joseph P, Worrall Bradford B, Furie Karen L, Kittner Steven J, Woo Daniel, Slowik Agnieszka, Meschia James F, Saxena Richa, Rosand Jonathan
Abstract excerpt
OBJECTIVE: Rare mitochondrial mutations cause neurologic disease, including ischemic stroke and MRI white matter changes. We investigated whether common mitochondrial genetic variants influence risk of sporadic ischemic stroke and, in patients with stroke, the volume of white matter hyperintensit...
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