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Article

Effect of itraconazole on the concentrations of tacrolimus and cyclosporine in the blood of patients receiving allogeneic hematopoietic stem cell transplants.

European journal of clinical pharmacology - 1 Jun 2013

Nara Miho, Takahashi Naoto, Miura Masatomo, Niioka Takenori, Kagaya Hideaki, Fujishima Naohito, Saitoh Hirobumi, Kameoka Yoshihiro, Tagawa Hiroyuki, Hirokawa Makoto, Sawada Kenichi

Abstract excerpt

PURPOSE: The purpose of this study was to investigate the interactions of itraconazole (ITCZ) with orally administered calcineurin inhibitors (CNIs) in Japanese allogeneic hematopoietic stem cell transplant (HSCT) recipients. METHODS: Sixteen HSCT patients (8 patients each receiving tacrolimus or cyclosporine) were enrolled. An ITCZ oral solution was administered from day 30 after the initiation of ITCZ...

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Identifiers

PMID: 23354810
DOI: 10.1007/s00228-013-1471-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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