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Article

Effects of cyclosporine a on single-dose pharmacokinetics of intravenous itraconazole in patients with hematologic malignancies.

Therapeutic drug monitoring - 1 Jun 2008

Timmers Gert Jan, Kessels Lonneke W, Wilhelm Abraham J, Veldkamp Agnes I, Bosch Tessa M, Beijnen Jos H, Huijgens Peter C

Abstract excerpt

An open-label, clinical pilot study was performed to study the effect of cyclosporine A (CsA) on single-dose pharmacokinetics of itraconazole in patients with a hematologic malignancy. Patients (n = 10), admitted for allogeneic stem cell transplantation, received a single dose of 200 mg itraconazole in a 1-hour intravenous infusion during their treatment period before initiation of CsA. This was repeated during...

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Identifiers

PMID: 18520601
DOI: 10.1097/FTD.0b013e318174e351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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