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Article

Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients.

Bone marrow transplantation - 1 Aug 2011

Onizuka M, Kunii N, Toyosaki M, Machida S, Ohgiya D, Ogawa Y, Kawada H, Inoko H, Ando K

Abstract excerpt

Calcineurin inhibitors are necessary as immunosuppressants during hematopoietic SCT (HSCT) to prevent alloreactivity, but have unfortunate toxicities. So, we investigated the association of gene polymorphisms with the initial calcineurin inhibitor concentration and the subsequent drug dose from d...

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Source

Identifiers

PMID: 21102498
DOI: 10.1038/bmt.2010.273

Genes

SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21102498-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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