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Article

Nicotine-motivated behavior in Caenorhabditis elegans requires the nicotinic acetylcholine receptor subunits acr-5 and acr-15.

The European journal of neuroscience - 1 Mar 2013

Sellings Laurie, Pereira Schreiber, Qian Cheng, Dixon-McDougall Thomas, Nowak Christina, Zhao Bin, Tyndale Rachel F, van der Kooy Derek

Abstract excerpt

Signaling at nicotinic acetylcholine receptors in Caenorhabditis elegans controls many behaviors, including egg-laying and locomotor activity. Here, we show that C. elegans approaches a point source of nicotine in a time-, concentration- and age-dependent manner. Additionally, nicotine paired with butanone under starvation conditions prevented the reduced approach to butanone that is observed when butanone is...

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Identifiers

PMID: 23351035
DOI: 10.1111/ejn.12099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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