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Article

eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx.

Genetics - 1 Jan 2004

McKay James P, Raizen David M, Gottschalk Alexander, Schafer William R, Avery Leon

Abstract excerpt

Mutations in eat-2 and eat-18 cause the same defect in C. elegans feeding behavior: the pharynx is unable to pump rapidly in the presence of food. EAT-2 is a nicotinic acetylcholine receptor subunit that functions in the pharyngeal muscle. It is localized to the synapse between pharyngeal muscle and the main pharyngeal excitatory motor neuron MC, and it is required for MC stimulation of pharyngeal muscle. eat-18...

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Identifiers

PMID: 15020415
DOI: 10.1534/genetics.166.1.161
PMCID: PMC1470703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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