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Article

GPA-14, a Gα(i) subunit mediates dopaminergic behavioral plasticity in C. elegans.

Behavioral and brain functions : BBF - 22 Apr 2013

Mersha Mahlet, Formisano Rosaria, McDonald Rochelle, Pandey Pratima, Tavernarakis Nektarios, Harbinder Singh

Abstract excerpt

BACKGROUND: Precise levels of specific neurotransmitters are required for appropriate neuronal functioning. The neurotransmitter dopamine is implicated in modulating behaviors, such as cognition, reward and memory. In the nematode Caenorhabditis elegans, the release of dopamine during behavioral plasticity is in part modulated through an acid-sensing ion channel expressed in its eight dopaminergic neurons. A...

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Identifiers

PMID: 23607404
DOI: 10.1186/1744-9081-9-16
PMCID: PMC3679979

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