Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biological stoichiometry in tumor micro-environments.

PloS one - 1 Jan 2013

Kareva Irina

Abstract excerpt

Tumors can be viewed as evolving ecological systems, in which heterogeneous populations of cancer cells compete with each other and somatic cells for space and nutrients within the ecosystem of the human body. According to the growth rate hypothesis (GRH), increased phosphorus availability in an ecosystem, such as the tumor micro-environment, may promote selection within the tumor for a more proliferative and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Cell Proliferation
Share to Models, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 23349677
DOI: 10.1371/journal.pone.0051844
PMCID: PMC3551943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biological stoichiometry in tumor micro-environments.PMID 23349677Read ↗

Do cell-autonomous and non-cell-autonomous effects drive the structure of tumor ecosystems?Semantic proximity Read ↗

A simulation of parental and glycolytic tumor phenotype competition predicts observed responses to pH changes and increased glycolysis after anti-VEGF therapy.Semantic proximity Read ↗

Ecology meets cancer biology: the cancer swamp promotes the lethal cancer phenotype.Semantic proximity Read ↗

Eco‐oncology: Applying ecological principles to understand and manage cancerSemantic proximity Read ↗

Models of tumor-host interaction as competing populations: implications for tumor biology and treatment.Semantic proximity Read ↗

Game-theoretical description of the go-or-grow dichotomy in tumor development for various settings and parameter constellations.Semantic proximity Read ↗

Non-cell-autonomous effects yield lower clonal diversity in expanding tumors.Semantic proximity Read ↗

Modeling tumors as species-rich ecological communitiesSemantic proximity Read ↗

The ecology of cancer from an evolutionary game theory perspectiveSemantic proximity Read ↗

Simulation Framework for Generating Intratumor Heterogeneity Patterns in a Cancer Cell PopulationSemantic proximity Read ↗

Modeling tumor progression in heterogeneous microenvironments: A cellular automata approach.Semantic proximity Read ↗

An agent-based model of avascular tumor growth: Immune response tendency to prevent cancer developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.