Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5.

Genesis (New York, N.Y. : 2000) - 1 Apr 2013

Ohtsuka Nobuhisa, Badurek Sylvia, Busslinger Meinrad, Benes Francine M, Minichiello Liliana, Rudolph Uwe

Abstract excerpt

Postmortem studies have revealed a downregulation of the transcription factor Pax5 in GABAergic neurons in bipolar disorder, a neurodevelopmental disorder, raising the question whether Pax5 in GABAergic neurons has a role in normal brain development. In a genetic approach to study functions of Pax5 in GABAergic neurons, Pax5 was specifically deleted in GABAergic neurons from Pax5 floxed mice using a novel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebral Ventricles
Share to Chromosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GABAergic Neurons

Share to Gene Dosage

Share to Hydrocephalus

Share to PAX5 Transcription Factor

Share to Penetrance

Share to Physical Chromosome Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 23349049
DOI: 10.1002/dvg.22370
PMCID: PMC3740952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5.PMID 23349049Read ↗

Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.Semantic proximity Read ↗

Compartmentalization and Interaction of Pax5 and Pax6 in Brain of MiceSemantic proximity Read ↗

Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.Semantic proximity Read ↗

Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in miceSemantic proximity Read ↗

Control of Neuronal Development by T-Box Genes in the Brain.Semantic proximity Read ↗

Scn1a-GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neuronsSemantic proximity Read ↗

Perinatal abrogation of Cdk5 expression in brain results in neuronal migration defectsSemantic proximity Read ↗

<i>Scn1a</i> -GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neuronsSemantic proximity Read ↗

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry.Semantic proximity Read ↗

An early Sox2-dependent gene expression program required for hippocampal dentate gyrus developmentSemantic proximity Read ↗

tubb5 knockout in zebrafish causes neurodevelopmental defects via notch pathways.Semantic proximity Read ↗

Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic NeuronsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.