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Article

Identification and functional annotation of genome-wide ER-regulated genes in breast cancer based on ChIP-Seq data.

Computational and mathematical methods in medicine - 1 Jan 2012

Ding Min, Wang Haiyun, Chen Jiajia, Shen Bairong, Xu Zhonghua

Abstract excerpt

Estrogen receptor (ER) is a crucial molecule symbol of breast cancer. Molecular interactions between ER complexes and DNA regulate the expression of genes responsible for cancer cell phenotypes. However, the positions and mechanisms of the ER binding with downstream gene targets are far from being fully understood. ChIP-Seq is an important assay for the genome-wide study of protein-DNA interactions. In this...

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Identifiers

PMID: 23346221
DOI: 10.1155/2012/568950
PMCID: PMC3546463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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