Article
[Clonal origin of multiple foci of urinary bladder cancer].
Arkhiv patologii - 1 Jan 2000
Babaian A Iu, Andreeva Iu Iu, Zaletaev D V, Nemtsova M V
Abstract excerpt
To analyze the pattern of molecular damages in urinary bladder cancer (UBC), the authors studied allelic imbalance of chromosome loci 9p21 and 17p13 in 22 patients diagnosed as having multiple primary UBC (2 to 5 foci in each patient). The state of markers has no informative value in 3 (13.6%) cases; in 9 (47.4%) of 19 informative cases, deletion of the same allele was determined in at least one of the loci in...
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