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Article

Determination of molecular markers for BRCA1 and BRCA2 heterozygosity using gene expression profiling.

Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2013

Salmon Asher Y, Salmon-Divon Mali, Zahavi Tamar, Barash Yulia, Levy-Drummer Rachel S, Jacob-Hirsch Jasmine, Peretz Tamar

Abstract excerpt

Approximately 5% of all breast cancers can be attributed to an inherited mutation in one of two cancer susceptibility genes, BRCA1 and BRCA2. We searched for genes that have the potential to distinguish healthy BRCA1 and BRCA2 mutation carriers from noncarriers based on differences in expression profiling. Using expression microarrays, we compared gene expression of irradiated lymphocytes from BRCA1 and BRCA2...

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Source

Identifiers

PMID: 23341570
DOI: 10.1158/1940-6207.CAPR-12-0105

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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