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Article

Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene.

Gastroenterology - 1 May 2013

Cui Shuang, Leyva-Vega Melissa, Tsai Ellen A, EauClaire Steven F, Glessner Joseph T, Hakonarson Hakon, Devoto Marcella, Haber Barbara A, Spinner Nancy B, Matthews Randolph P

Abstract excerpt

BACKGROUND & AIMS: Biliary atresia (BA) is a progressive fibroinflammatory disorder of infants involving the extrahepatic and intrahepatic biliary tree. Its etiology is unclear but is believed to involve exposure of a genetically susceptible individual to certain environmental factors. BA occurs exclusively in the neonatal liver, so variants of genes expressed during hepatobiliary development could affect...

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Source

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Identifiers

PMID: 23336978
DOI: 10.1053/j.gastro.2013.01.022
PMCID: PMC3736559

Genes

GPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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