Article
Genome-wide association studies in biliary atresia.
Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000
Ningappa Mylarappa, Min Jun, Higgs Brandon W, Ashokkumar Chethan, Ranganathan Sarangarajan, Sindhi Rakesh
Abstract excerpt
Biliary atresia (BA) is a model complex disease resulting from interactions between multiple susceptibility loci and environmental factors. This perception is based on a heterogeneous phenotype extending beyond an absent extrahepatic bile duct to include gut and cardiovascular anomalies, and the association of BA with viral infections. Refractory jaundice and progression to cirrhosis shortly after birth can be...
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