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Article

Common genetic variants of GPC1 gene reduce risk of biliary atresia in a Chinese population.

Journal of pediatric surgery - 1 Oct 2016

Ke Juntao, Zeng Shuaidan, Mao Jianxiong, Wang Jianyao, Lou Jiao, Li Jiaoyuan, Chen Xueqin, Liu Cheng, Huang Liu-Ming, Wang Bin, Liu Lei

Abstract excerpt

BACKGROUND: Biliary atresia (BA) is a major neonatal cholestatic disease and main indication for pediatric liver transplantation in the world. Recently, GPC1 has been implicated as a risk gene for BA by genetic studies and follow-up functional experiments on zebrafish. METHODS: Two common genetic variants of GPC1, rs2292832 and rs3828336, were selected systematically through 'SNPinfo', and were examined using...

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Source

Identifiers

PMID: 27373597
DOI: 10.1016/j.jpedsurg.2016.05.009

Genes

GPC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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