Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.

PloS one - 1 Jan 2013

Müller Anne, Kleinau Gunnar, Piechowski Carolin L, Müller Timo D, Finan Brian, Pratzka Juliane, Grüters Annette, Krude Heiko, Tschöp Matthias, Biebermann Heike

Abstract excerpt

The G-protein coupled receptor 83 (GPR83) is an orphan G-protein coupled receptor for which the natural ligand(s) and signaling pathway(s) remain to be identified. Previous studies suggest a role of GPR83 in the regulation of thermogenesis and the control of circulating adiponectin. The aim of th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Chlorides
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to HEK293 Cells

Share to Molecular Docking Simulation

Share to Protein Multimerization

Share to Receptors, G-Protein-Coupled

Source

Open in PubMed Open full text

Identifiers

PMID: 23335960
DOI: 10.1371/journal.pone.0053347
PMCID: PMC3546042

Genes

GPR83

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23335960-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.PMID 23335960Read ↗

The extracellular N-terminal domain of G-protein coupled receptor 83 regulates signaling properties and is an intramolecular inverse agonist.Semantic proximity Read ↗

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.Semantic proximity Read ↗

Signaling pathway mechanisms of neurological diseases induced by G protein‐coupled receptor 39Semantic proximity Read ↗

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.Semantic proximity Read ↗

ZIP13/SLC39A13 integrates intracellular iron distribution with adipose energy metabolismSemantic proximity Read ↗

Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82.Semantic proximity Read ↗

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular diseaseSemantic proximity Read ↗

GPR39, a receptor of the ghrelin receptor family, plays a role in the regulation of glucose homeostasis in a mouse model of early onset diet-induced obesity.Semantic proximity Read ↗

Two naturally occurring mutations of human GPR103 define distinct G protein selection bias.Semantic proximity Read ↗

Adaptive evolution of GPR39 in diverse directions in vertebrates.Semantic proximity Read ↗

G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms.Semantic proximity Read ↗

GPR35 as a Novel Therapeutic TargetSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.