Article
Allelic and genotypic frequencies of platelet glycoprotein polymorphisms in a Portuguese population.
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology - 1 Feb 2013
Pina-Cabral Luís Bernardo, Carvalhais Virgínia, Mesquita Bárbara, Escórcio Claudia, Salgado Paula, Santos Amândia, Ruivães Ema, Monteiro Maria Céu, Arrieta Isabel, O'Connor Enrique, Almeida-Dias António, Criado Begoña
Abstract excerpt
INTRODUCTION AND OBJECTIVES: We studied genotypic and allelic frequencies of polymorphisms that can affect platelet function, namely the Kozak, VNTR and HPA-2 polymorphisms of glycoprotein Ibα, the Pl(A) polymorphism of glycoprotein IIIa and the C807T polymorphism of glycoprotein Ia, in a Portuguese population composed of 227 donors. METHODS: PCR-RFLP was used to assess the Kozak, HPA-2, Pl(A) and C807T...
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