Platelet glycoprotein Ia 807C/T (Phe224) and 873G/A (Thr246) dimorphisms in Turkey.

doi:10.1002/ajh.10029

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Article

Platelet glycoprotein Ia 807C/T (Phe224) and 873G/A (Thr246) dimorphisms in Turkey.

American journal of hematology - 1 Jan 2002

Komurcu Evrim, Erginel-Unaltuna Nihan

Abstract excerpt

At sites of vascular injury, the platelet collagen receptor Glycoprotein Ia/IIa (GPIa/IIa) acts as an important mediator of platelet adhesion to fibrillar collagens. Two silent polymorphisms (807C/T and 873G/A) within the glycoprotein Ia gene have been implicated in increased risk of developing thrombosis and myocardial infarction in affected individuals. To provide basis for future studies, we examined the...

Topics

Alleles
DNA
Female
Gene Frequency
Genotype
Humans
Integrins
Leukocytes
Male
Phenylalanine
Platelet Membrane Glycoproteins
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, Collagen
Threonine
Turkey

Source

Open in PubMed

Identifiers

PMID: 11835340
DOI: 10.1002/ajh.10029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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