Article

Lipid signalling dynamics of palmitate-induced endoplasmic reticulum stress in skeletal muscle

2019-01-01

Abstract excerpt

Approximately 340 million people worldwide have Type 2 Diabetes Mellitus (T2DM), making identification of the aetiological processes underlying this disease imperative. Endoplasmic reticulum (ER) stress has emerged as a potential mechanism driving the pathogenesis of obesity and T2DM. Palmitate, the predominant saturated fatty acid elevated in the blood plasma of obese individuals, induces ER stress and insulin re...

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Literature Corpus work: 9507ff40-337f-5217-8497-675d0df4123d
DOI: 10.17863/cam.40014

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