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Article

Epistatic connectivity among HCV genomic sites as a genetic marker of interferon resistance.

Antiviral therapy - 1 Jan 2012

Lara James, Khudyakov Yury

Abstract excerpt

Until recently, the standard-of-care therapy of patients with HCV infection involves treatment with interferon (IFN) and ribavirin (RBV). Host demographic and genetic factors as well as HCV genetic heterogeneity have been shown to be associated with outcomes of therapy. Although resistance to IFN/RBV remains an important clinical and public health problem, there are no reliable genetic markers for the prediction...

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Share to Antiviral Agents
Share to Drug Resistance, Viral
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Genome, Viral

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Share to Interferons

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Source

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Identifiers

PMID: 23321567
DOI: 10.3851/IMP2478
PMCID: PMC5762110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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