Article
Association of HLA-DRB1 single nucleotide polymorphisms with left ventricular remodelling in elderly patients with essential hypertension.
The Journal of international medical research - 1 Jan 2012
Li Q M, Li B, Sun Y F, Zhang H, Yang X L, Cai L W, Chen H, Ding Y H, Jiang J
Abstract excerpt
OBJECTIVE: To investigate the associations between human leucocyte antigen DRβ1 (HLA-DRB1) gene polymorphisms and cardiovascular remodelling (left ventricular dilatation [LVD]) in Han Chinese patients ≥ 60 years old, with essential hypertension. METHODS: LVD was diagnosed via echocardiographic measurements. Multiplex polymerase chain reaction-ligase detection reaction was used to determine the genotypes of three...
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