Article
The gene polymorphism of LOX1 predicts the incidence of LVH in patients with essential hypertension.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2014
Xu Xiaolin, Hou Xuwei, Liang Yixiu, Li Fan, Pang Liewen, Huang Guoqian, Huang Jiechun, Shi Meng, Sun Xiaotian, Wang Yiqing
Abstract excerpt
BACKGROUND: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) has been shown to play an important role in cardiac remodeling under different pathologic conditions. The role of genetic polymorphisms in the LOX1 gene, however, remains unclear in the development of left ventricular hypertrophy (LVH) for patients with hypertension. METHODS: A total of 536 patients diagnosed with essential hypertension...
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